SCHEMBL35327

SCHEMBL35327

c1ccc(-c2ccnc3ccccc23)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.60
MAPK14 Q16539 1/20 0.60
PIK3CA P42336 1/20 0.59
GRM4 Q14833 6/20 0.58
HTR2B P41595 1/20 0.58
MTNR1A P48039 1/20 0.58
KCNH2 Q12809 1/20 0.58
CYP1A2 P05177 1/20 0.53
BMP4 P12644 1/20 0.53
NCF1 P14598 1/20 0.52
ACVR1 Q04771 5/20 0.52
AURKB Q96GD4 2/20 0.52
IKBKB O14920 1/20 0.52
CHUK O15111 1/20 0.52
DAPK3 O43293 1/20 0.52
JAK2 O60674 1/20 0.52
PRKD3 O94806 1/20 0.52
MAP4K4 O95819 1/20 0.52
PAK4 O96013 1/20 0.52
CSF1R P07333 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30439957 1.00 TGFBR1 (0.60) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL12074333 0.96 PIK3CA (0.65) TGFBR1MAPK14PIK3CAGRM4HTR2B
Formaldehyde SCHEMBL27672857 0.94 TGFBR1 (0.55) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL12580413 0.89 PIK3CA (0.54) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL12580359 0.89 PIK3CA (0.54) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL4658401 0.88 CA12 (0.59) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL27898092 0.88 PIK3CA (0.65) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL21131938 0.88 PIK3CA (0.53) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL12580372 0.88 PIK3CA (0.56) TGFBR1MAPK14PIK3CAGRM4HTR2B
SCHEMBL12580422 0.88 PIK3CA (0.56) TGFBR1MAPK14PIK3CAGRM4HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117487537-A In-situ activated room temperature long afterglow luminous SiO 2 Nanometer material, preparation method and application thereof 西北工业大学 2024-02-02 CN claimed
CN-113620934-B Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2023-07-07 CN claimed
CN-111825722-B Saturated red-light-emitting fluorenyl benzoquinoline iridium complex 北京印刷学院 2023-06-09 CN claimed
CN-111116466-B Catalytic synthesis method of polysubstituted quinoline derivative 浙江万里学院 2023-02-10 CN claimed
CN-113620934-A Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-11-09 CN claimed
CN-112939857-A Synthetic method of alkylated quinoline compound 中国科学院大连化学物理研究所 2021-06-11 CN claimed
CN-112047882-A New application of isoquinoline and quinoline derivatives in preparation of blood fat reducing drugs 天津科技大学 2020-12-08 CN claimed
CN-106946776-B A kind of 4- phenylchinoline class compound, preparation method and application 贾忠 2019-11-08 CN claimed
CN-109776413-A Isoquinoline derivative with hypoglycemic activity and application 天津科技大学 2019-05-21 CN claimed
CN-107082765-A A kind of synthetic method of the phenylquinazoline of 2 chlorine 4 常州大学 2017-08-22 CN claimed
EP-2433121-A1 THERMALLY STABLE SERS TAGGANTS Cabot Security Materials Inc. (US) 2012-03-28 EP claimed
US-20120062886-A1 Thermally Stable SERS Taggants CABOT SECURITY MATERIALS INC. (US) 2012-03-15 US claimed
WO-2010135351-A1 THERMALLY STABLE SERS TAGGANTS OXONICA MATERIALS INC. (US) 2010-11-25 WO claimed
CN-1459483-A Blue coloured electroluminous organic film and its preparation method CHINESE ACAD INST CHEMISTRY (CN) 2003-12-03 CN claimed
WO-1991008188-A1 PROCESS FOR THE PREPARATION OF 4-PHENYLQUINOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-13 WO claimed
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP claimed
US-4945183-A OXIDATION OF BIPHENYL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-31 US claimed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP claimed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US claimed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP claimed