Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16068702 | 0.89 | KMT2A (0.43) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL1432899 | 0.86 | CYP3A4 (0.47) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL8934106 | 0.84 | LMNA (0.50) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL8590498 | 0.84 | LMNA (0.46) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL8590501 | 0.84 | LMNA (0.46) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL4510815 | 0.83 | NR3C2 (0.54) | NR3C1NR3C2 | |
| SCHEMBL28112501 | 0.83 | NR3C1 (0.45) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL30369402 | 0.83 | LMNA (0.49) | LMNATP53HTTMEN1KMT2A | |
| SCHEMBL15075786 | 0.83 | ABL1 (0.54) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL25914601 | 0.83 | LMNA (0.53) | LMNATP53HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781439-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2010-08-24 | — | — | US | disclosed |
| US-20080287463-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | US | disclosed |
| EP-1853607-A2 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087120-A2 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287463-A1 | Pyrazolopyrimidines | RRP15, RPLP2, DPYD | LMNA 4262/4885TP53 1185/4885HTT 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.