Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531635 | 0.96 | HTR6 (0.44) | HTR6DRD2HTR2CHTR2BHTR1B | |
| Hydrochloric Acid SCHEMBL3528624 | 0.91 | HTR6 (0.41) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3529165 | 0.90 | HTR6 (0.43) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3535899 | 0.89 | TP53 (0.43) | HTR6DRD2HTR1BHTR1DSLC6A9 | |
| SCHEMBL13342338 | 0.89 | HTR6 (0.45) | HTR6DRD2HTR2CHTR2B | |
| SCHEMBL3532795 | 0.88 | HTR6 (0.45) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3529592 | 0.88 | HTR1B (0.44) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3532480 | 0.87 | HTR6 (0.45) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3532484 | 0.87 | HTR6 (0.44) | HTR6DRD2HTR2CHTR2BHTR1B | |
| SCHEMBL3529593 | 0.86 | HTR6 (0.44) | HTR6DRD2HTR2CHTR2BHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723329-B2 | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH LLC (US) | 2010-05-25 | — | — | US | claimed |