SCHEMBL353379

SCHEMBL353379

Brc1cccc(-c2ccccn2)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.71
LMNA P02545 4/20 0.71
ALOX15 P16050 4/20 0.71
L3MBTL1 Q9Y468 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
CCR1 P32246 3/20 0.71
CCR5 P51681 3/20 0.71
CCR8 P51685 3/20 0.71
TP53 P04637 3/20 0.71
TDP1 Q9NUW8 3/20 0.71
HTT P42858 2/20 0.71
ALPL P05186 2/20 0.71
HSP90AA1 P07900 1/20 0.71
ALPI P09923 1/20 0.71
ALPG P10696 1/20 0.71
MAPK1 P28482 1/20 0.71
METAP1 P53582 2/20 0.61
CYP1A2 P05177 1/20 0.61
POLB P06746 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29946428 1.00 KDM4E (0.71) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL30485904 1.00 KDM4E (0.71) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL994004 0.98 KDM4E (0.75) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL1456808 0.92 RAB9A (0.67) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
Phenanthroline SCHEMBL22042790 0.88 KDM4E (0.55) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL12257971 0.86 SMN1; SMN2 (0.58) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL15249622 0.86 SMN1; SMN2 (0.58) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
Terpyridine SCHEMBL57442 0.84 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL7964803 0.84 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL30172832 0.84 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP claimed
CN-119013558-A Photoactivated antibody conjugates 新析生物科技股份有限公司 2024-11-22 CN claimed
CN-116496324-B Ruthenium complex, preparation method thereof and application thereof in alkylation reaction of indole and alcohol 河北师范大学 2024-10-18 CN claimed
CN-118142589-A Catalyst for co-production of dimethyl oxalate and dimethyl carbonate, preparation method and application thereof 河南能源集团研究总院有限公司 2024-06-07 CN claimed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO claimed
CN-116496324-A Ruthenium complex, preparation method thereof and application thereof in alkylation reaction of indole and alcohol 河北师范大学 2023-07-28 CN claimed
CN-113663733-B Preparation and application of graphene covalent supported bipyridine metal complex catalyst 合肥工业大学 2023-06-06 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-115477661-A Trinuclear pyridine copper complex and preparation method and application thereof 云南师范大学 2022-12-16 CN claimed
CN-113663733-A Preparation and application of graphene covalent load bipyridine metal complex catalyst 合肥工业大学 2021-11-19 CN claimed
CN-112047925-A Preparation method of N- (aryl/heteroaryl) alkyl-diamide 中国科学院兰州化学物理研究所 2020-12-08 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US disclosed
EP-4026881-B1 ORGANIC THIN FILM AND METHOD FOR PRODUCING ORGANIC THIN FILM JAPAN BROADCASTING CORP (JP) 2025-07-30 EP disclosed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO disclosed
EP-0588146-B1 Substituted pyridin derivatives and parasiticides containing them BASF AG (DE) 1998-11-11 EP disclosed
US-5346899-A Fungicides especially effective against ascomycetes and basidomycetes BASF AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
EP-0588146-A2 Substituted pyridin derivatives and parasiticides containing them BASF Aktiengesellschaft (DE) 1994-03-23 EP disclosed