SCHEMBL994004

SCHEMBL994004

Brc1cccc(-c2cccc(-c3ccccn3)n2)n1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.75
LMNA P02545 4/20 0.75
ALOX15 P16050 4/20 0.75
L3MBTL1 Q9Y468 4/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
CCR1 P32246 3/20 0.75
CCR5 P51681 3/20 0.75
CCR8 P51685 3/20 0.75
TP53 P04637 3/20 0.75
TDP1 Q9NUW8 3/20 0.75
HTT P42858 2/20 0.75
ALPL P05186 2/20 0.75
HSP90AA1 P07900 1/20 0.75
ALPI P09923 1/20 0.75
ALPG P10696 1/20 0.75
MAPK1 P28482 1/20 0.75
METAP1 P53582 2/20 0.58
CYP1A2 P05177 1/20 0.58
POLB P06746 1/20 0.58
BLM P54132 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353379 0.98 KDM4E (0.71) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL30485904 0.98 KDM4E (0.71) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL29946428 0.98 KDM4E (0.71) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL1456808 0.90 RAB9A (0.67) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL12257971 0.88 SMN1; SMN2 (0.58) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL15249622 0.88 SMN1; SMN2 (0.58) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL7964803 0.87 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
Terpyridine SCHEMBL29357603 0.87 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
Terpyridine SCHEMBL57442 0.87 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2
SCHEMBL30172832 0.87 KDM4E (1.00) KDM4ELMNAALOX15L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12258353-B2 Heterocyclic compound and organic light-emitting element including same LT MATERIALS CO., LTD. (KR) 2025-03-25 US disclosed
CN-113166171-B Heterocyclic compound and organic light-emitting device comprising the same LT素材株式会社 2024-05-14 CN disclosed
US-11697663-B2 Metal-ligand catalysts for selective promotion of electrochemical CO2RR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-11 US disclosed
US-20220033415-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME LT MATERIALS CO., LTD. (KR) 2022-02-03 US disclosed
US-20210238212-A1 METAL-LIGAND CATALYSTS FOR SELECTIVE PROMOTION OF ELECTROCHEMICAL CO2RR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 US disclosed
CN-113166171-A Heterocyclic compound and organic light-emitting device comprising the same LT素材株式会社 2021-07-23 CN disclosed
WO-2021129639-A1 ORGANIC COMPOUND AND APPLICATION, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING ORGANIC COMPOUND 陕西莱特光电材料股份有限公司 2021-07-01 WO disclosed
WO-2020116995-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME 엘티소재주식회사 2020-06-11 WO disclosed
US-8716698-B2 Organic electroluminescent device containing arylamine compound and bipyridyl compound HODOGAYA CHEMICAL CO., LTD. (JP) 2014-05-06 US disclosed
US-8642189-B2 Substituted bipyridyl compound and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-04 US disclosed
EP-2540707-A1 SUBSTITUTED PYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2013-01-02 EP disclosed
US-20120319098-A1 SUBSTITUTED PYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT SHINSHU UNIVERSITY (JP) 2012-12-20 US disclosed
US-20120161107-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO, LTD (JP) 2012-06-28 US disclosed
EP-2299510-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2011-03-23 EP disclosed
US-20110001129-A1 SUBSTITUTED BIPYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2011-01-06 US disclosed
EP-2269987-A1 SUBSTITUTED BIPYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2011-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110001129-A1 SUBSTITUTED BIPYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE ETV6, KCNH3, CTCF KDM4E 781/4885LMNA 2934/4885ALOX15 2362/4885
US-20210238212-A1 METAL-LIGAND CATALYSTS FOR SELECTIVE PROMOTION OF ELECTROCHEMICAL CO2RR SPR, TPR, CPNE4 KDM4E 3103/4885LMNA 4884/4885ALOX15 4435/4885
US-20120319098-A1 SUBSTITUTED PYRIDYL COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT PNPO, PLPBP, SLC19A2 KDM4E 1892/4885LMNA 2483/4885ALOX15 1467/4885
US-20220033415-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME CRY1, CRY2, LEF1 KDM4E 2194/4885LMNA 3542/4885ALOX15 152/4885
US-11697663-B2 Metal-ligand catalysts for selective promotion of electrochemical CO2RR SPR, TPR, CPNE4 KDM4E 3103/4885LMNA 4884/4885ALOX15 4435/4885
US-12258353-B2 Heterocyclic compound and organic light-emitting element including same CRY1, CRY2, LEF1 KDM4E 2194/4885LMNA 3542/4885ALOX15 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.