Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075352 | 0.89 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL28077771 | 0.87 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL28113853 | 0.84 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3535215 | 0.83 | — | — | |
| SCHEMBL28657140 | 0.80 | — | — | |
| SCHEMBL5693026 | 0.79 | GLO1 (0.31) | — | |
| SCHEMBL5443235 | 0.78 | — | — | |
| SCHEMBL5011756 | 0.75 | — | — | |
| SCHEMBL7160851 | 0.75 | — | — | |
| SCHEMBL18683149 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478729-B1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | NUTRASWEET CO (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0478729-A4 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | — | 1993-06-16 | — | — | EP | claimed |
| EP-0478729-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR. | NUTRASWEET CO (US) | 1992-04-08 | — | — | EP | claimed |
| WO-1991014378-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | THE NUTRASWEET COMPANY (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0083613-B1 | N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | MAY & BAKER LIMITED (GB) | 1988-06-01 | — | — | EP | claimed |
| US-12351570-B2 | Disubstituted alkyne derivatives | MERCK PATENT GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | disclosed |
| EP-3898588-B1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-01-11 | — | — | EP | disclosed |
| WO-2021249969-A1 | COMBINATION PRODUCT FOR THE TREATMENT OF CANCER DISEASES | MERCK PATENT GMBH (DE) | 2021-12-16 | — | — | WO | disclosed |
| EP-3898588-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | Merck Patent GmbH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127960-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-7807837-B2 | Scalable synthesis of imidazole derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-05 | — | — | US | disclosed |
| US-4283396-A | 3-Acetoxymethyl-7-(hydroxyiminoacetamido)-cephalosporanic acid derivatives | ROUSSEL UCLAF (FR) | 1981-08-11 | — | — | US | disclosed |
| US-4196205-A | ANTIBIOTICS, BACTERICIDES | ROUSSEL UCLAF (FR) | 1980-04-01 | — | — | US | disclosed |
| US-4195025-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0003883-A1 | Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals | ELI LILLY AND COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| EP-0002859-A2 | 3,4-Methano pyrrolidine derivatives, compositions thereof and use as plant-growth regulating agents | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-07-11 | — | — | EP | disclosed |
| US-4152450-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4152432-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1979-05-01 | — | — | US | disclosed |
| US-3937837-A | SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS | WARNER-LAMBERT COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351570-B2 | Disubstituted alkyne derivatives | BRCA1, MYC, PCNA | ALDH1A1 414/4885 |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | BRCA1, MYC, PCNA | ALDH1A1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.