Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531206 | 0.81 | NR3C1 (0.62) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL3531203 | 0.81 | NR3C1 (0.62) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL3536940 | 0.79 | NR3C1 (0.36) | NR3C1PGR | |
| SCHEMBL1714034 | 0.74 | NR3C1 (0.81) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL12893346 | 0.74 | NR3C1 (0.81) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL12893347 | 0.74 | NR3C1 (0.81) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL14422072 | 0.74 | NR3C1 (0.81) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL3533059 | 0.73 | NR3C1 (0.63) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL3533060 | 0.73 | NR3C1 (0.63) | NR3C1PGRARL3MBTL1 | |
| SCHEMBL3533057 | 0.73 | NR3C1 (0.63) | NR3C1PGRARL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662821-B2 | improved selectivity and pharmacokinetic properties; 6-Fluoro-1-[(1 H-indazol-4-yl)amino]-4,4-dimethyl-2-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene-2,5-diol; cyclization of imines | BAYER SCHERING PHARMA AG (DE) | 2010-02-16 | — | — | US | claimed |
| EP-1670458-B1 | 1-AMINO-2-OXY-SUBSTITUTED TETRAHYDRONAPHTALENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS | SCHERING AG (DE) | 2006-12-20 | — | — | EP | disclosed |