Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537548 | 0.79 | — | — | |
| Butane SCHEMBL6847120 | 0.72 | — | — | |
| SCHEMBL7130265 | 0.71 | — | — | |
| SCHEMBL264243 | 0.65 | — | — | |
| SCHEMBL214833 | 0.65 | — | — | |
| SCHEMBL6590316 | 0.63 | — | — | |
| SCHEMBL104305 | 0.63 | — | — | |
| SCHEMBL4741885 | 0.63 | — | — | |
| Methane SCHEMBL9705790 | 0.63 | — | — | |
| SCHEMBL27623259 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3775957-A1 | MATERIALS WITH HIGH DIELECTRIC CONSTANT FOR MAGNETIC RESONANCE IMAGING INSTRUMENTS | Centre National de la Recherche Scientifique - CNRS (FR) | 2021-02-17 | — | — | EP | claimed |
| CN-117545754-A | Modulators of TREX1 | 星座制药公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-111574464-A | Quinazoline derivatives for the treatment of HIV | 吉利德科学公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-107278201-B | Quinazoline derivatives for the treatment of HIV | 吉利德科学公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-102361851-B | Method for producing cyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL CO | 2014-03-19 | — | — | CN | disclosed |
| EP-1940401-B1 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2012-07-11 | — | — | EP | disclosed |
| CN-102361851-A | Method for producing cyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL CO | 2012-02-22 | — | — | CN | disclosed |
| US-7652024-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2010-01-26 | — | — | US | disclosed |
| US-20090325990-A1 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2009-12-31 | — | — | US | disclosed |
| EP-1940401-A2 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007148808-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007047496-A2 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| CN-1249023-C | Ester compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2006-04-05 | — | — | CN | disclosed |
| US-6908945-B2 | Ester compound and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-21 | — | — | US | disclosed |
| CN-1451650-A | Ester compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2003-10-29 | — | — | CN | disclosed |
| US-20030195119-A1 | 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 2-(2-cyanopropenyl)-3,3-dimethylcyclopropanecarboxylate; pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-0745586-B1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-08 | — | — | EP | disclosed |
| EP-0745586-A1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |
| US-4431576-A | COSMETICS; TOILETRIES; DETERGENTS; INSECTICIDES; WAXES | ROUSSEL UCLAF (FR) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325990-A1 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MC4R, MC5R, MC3R | TSHR 367/4885 |
| US-20030195119-A1 | 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 2-(2-cyanopropenyl)-3,3-dimethylcyclopropanecarboxylate; pesticides | DDT, CASP3, CASP2 | TSHR 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.