SCHEMBL35385

SCHEMBL35385

C=C(C)C(=O)OC(CO)CO

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
THRB P10828 1/20 0.38
TGFBR1 P36897 1/20 0.36
PRKCA P17252 4/20 0.35
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL20787977 0.94 TSHR (0.41) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL159608 0.89 TSHR (0.41) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL11000160 0.87 TSHR (0.39) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL11343999 0.87 TSHR (0.39) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL7631606 0.87 TSHR (0.39) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL11345676 0.87 TSHR (0.39) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL8022030 0.87 TSHR (0.39) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL11049715 0.86 ALDH1A1 (0.41) TSHRALDH1A1MAPTMAPK1THRB
SCHEMBL14944 0.86 TSHR (0.57) TSHRTHRBPRKCA
SCHEMBL9340152 0.84 LMNA (0.43) TSHRALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7951 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
WO-2026099827-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC. (CH) 2026-05-15 WO claimed
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC (CH) 2026-05-14 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
EP-4736243-A1 (METH)ACRYLATE POLYMERS AS ADDITIVES IN BATTERY ELECTRODES Syensqo Specialty Polymers Italy S.p.A. (IT) 2026-05-06 EP claimed
US-20260118553-A1 METHOD OF PREPARING SURFACE-MODIFIED CONTACT LENS AND METHOD OF MODIFYING SURFACE OF POLYMERIC MATERIAL NATIONAL YANG MING CHIAO TUNG UNIV (TW) 2026-04-30 US claimed
EP-2828317-B1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR PREPARATION THEREOF AND THIN FILMS CONTAINING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2026-04-29 EP claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713720-A2 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS Alcon Inc. (CH) 2026-03-25 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0401990-A2 Prepolymers useful in biomedical devices BAUSCH & LOMB INCORPORATED (US) 1990-12-12 EP claimed
US-4751263-A IMPROVED CURE SPEED, FLEXIBILITY UNION CARBIDE CORPORATION (US) 1988-06-14 US claimed
EP-0216074-A2 Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
EP-0054249-B1 IMMUNOPARTICLES AND PROCESS FOR PREPARING THE SAME TORAY INDUSTRIES, INC. (JP) 1985-07-03 EP claimed
EP-0075957-A2 Curable molding compositions containing a poly(acrylate) UNION CARBIDE CORPORATION (US) 1983-04-06 EP claimed
EP-0069340-A1 Curable molding compositions containing a poly(acrylate) UNION CARBIDE CORPORATION (US) 1983-01-12 EP claimed
EP-0054249-A1 Immunoparticles and process for preparing the same TORAY INDUSTRIES, INC. (JP) 1982-06-23 EP claimed
US-4038264-A HYDROPHILIC POLYACRYLIC ESTERS, CONTACT LENSES NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-07-26 US claimed
US-3954966-A Infusion solutions and method of manufacturing same CESKOSLOVENSKA AKADEMIE VED (CS) 1976-05-04 US claimed