SCHEMBL353864

SCHEMBL353864

CC(C)(C)NCCCS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
POLB P06746 1/20 0.37
EPHX2 P34913 1/20 0.35
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
SLC6A6 P31641 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.32
TP53BP1 Q12888 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4412454 0.98 APP (0.39) APPPOLBEPHX2HRH4HRH3
SCHEMBL353687 0.95 APP (0.41) APPPOLBEPHX2HRH4HRH3
SCHEMBL22800827 0.93 EPHX2 (0.41) APPPOLBEPHX2HRH4HRH3
SCHEMBL918752 0.86 LMNA (0.36) APPPOLBEPHX2LMNABLM
SCHEMBL4972929 0.84 APP (0.39) APPEPHX2LMNABLMPTGS1
SCHEMBL4404059 0.84 LMNA (0.35) APPPOLBLMNABLMPTGS1
SCHEMBL12248067 0.81 APP (0.37) APPEPHX2LMNABLMPTGS1
SCHEMBL21787654 0.81 APP (0.37) APPEPHX2LMNABLMPTGS1
SCHEMBL11245300 0.81 APP (0.37) APPEPHX2LMNABLMPTGS1
SCHEMBL918261 0.81 EPHX1 (0.37) APPEPHX2LMNABLMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291874-A1 METHODS FOR MAKING AND USING NOVEL FOAMER COMPOSITIONS WEATHERFORD TECHNOLOGY HOLDINGS, LLC 2015-10-15 US claimed
US-9018145-B2 Foamer composition and methods for making and using same Lubrizol Oilfield Solutions, Inc. (US) 2015-04-28 US claimed
US-8714283-B2 Foamer/sulfur scavenger composition and methods for making and using same CLEARWATER INTERNATIONAL, LLC (US) 2014-05-06 US claimed
US-20120088697-A1 FOAMER/SULFUR SCAVENGER COMPOSITION AND METHODS FOR MAKING AND USING SAME WEATHERFORD/LAMB, INC. 2012-04-12 US claimed
US-7906109-B2 Pharmaceutical composition comprising an active principal and sulphobetaine LEK PHARMACEUTICALS D.D. (SL) 2011-03-15 US claimed
CN-100528840-C Improved drug candidates and methods for their preparation NEUROCHEM INTERNAT LTD (CH) 2009-08-19 CN claimed
EP-1729794-B1 A PHARMACEUTICAL COMPOSITION COMPRISING A NON-DETERGENT SULPHOBETAINE LEK PHARMACEUTICALS (SI) 2008-07-09 EP claimed
US-20080027097-A1 PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2008-01-31 US claimed
US-20070184019-A1 Pharmaceutical composition comprising an active principal and sulphobetaine LEK PHARMACEUTICALS D.D. (SI) 2007-08-09 US claimed
US-7253306-B2 Pharmaceutical drug candidates and methods for preparation thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-08-07 US claimed
WO-2005007895-A1 METHODS AND KITS FOR OBTAINING NUCLEIC ACID FROM BIOLOGICAL SAMPLES APPLERA CORPORATION (US) 2005-01-27 WO claimed
US-20050009036-A1 Methods and kits for obtaining nucleic acid from biological samples APPLERA CORPORATION (US) 2005-01-13 US claimed
WO-2004113391-A2 IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2004-12-29 WO claimed
EP-0972333-B1 METHODS AND SYSTEMS FOR ENHANCED FLUID TRANSPORT CALIPER LIFE SCIENCES INC (US) 2004-11-24 EP claimed
US-6129826-A APPARATUS FOR ENHANCING TRANSPORT AND DIRECTION OF MATERIALS IN FLUIDIC SYSTEMS UTILIZING ELECTROOSMOTIC FLOW SYSTEMS, BY ADDING ZWITTERIONIC COMPOUND(S) TO THE FLUID CONTAINING THE MATERIAL TO BE TRANSPORTED OR DIRECTED CALIPER TECHNOLOGIES CORP. (US) 2000-10-10 US claimed
EP-0972333-A4 METHODS AND SYSTEMS FOR ENHANCED FLUID TRANSPORT CALIPER TECHN CORP (US) 2000-06-28 EP claimed
EP-0972333-A1 METHODS AND SYSTEMS FOR ENHANCED FLUID TRANSPORT Caliper Technologies Corporation (US) 2000-01-19 EP claimed
US-5964995-A ENHANCING MATERIAL DIRECTION AND TRANSPORT BY ELECTROOSMOTIC FLOW OF A FLUID CONTAINING THAT MATERIAL BY ADDING A ZWITTERIONIC COMPOUND; REDUCING ELECTROPHORETIC SEPARATION OF DIFFERENTIALLY CHARGED SPECIES IN A MICROSCALE FLUID COLUMN CALIPER TECHNOLOGIES CORP. (US) 1999-10-12 US claimed
WO-1998045929-A9 METHODS AND SYSTEMS FOR ENHANCED FLUID TRANSPORT 1999-03-11 WO claimed
WO-1998045929-A1 METHODS AND SYSTEMS FOR ENHANCED FLUID TRANSPORT CALIPER TECHNOLOGIES CORPORATION (US) 1998-10-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070184019-A1 Pharmaceutical composition comprising an active principal and sulphobetaine SCN2B, SCN1B, SPTSSB APP 2443/4885POLB 367/4885EPHX2 2748/4885
US-20080027097-A1 PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF MPST, TTR, STS APP 86/4885POLB 3707/4885EPHX2 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.