Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540820 | 1.00 | ALDH1A1 (0.52) | ALDH1A1PDK2FKBP1AHSD11B1ROCK2 | |
| SCHEMBL3540732 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HSD11B1ROCK2MAPK1L3MBTL1 | |
| SCHEMBL3540729 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HSD11B1ROCK2MAPK1L3MBTL1 | |
| SCHEMBL3547665 | 0.85 | FKBP1A (0.51) | ALDH1A1PDK2FKBP1AROCK2KMT2A | |
| SCHEMBL3547667 | 0.85 | FKBP1A (0.51) | ALDH1A1PDK2FKBP1AROCK2KMT2A | |
| SCHEMBL3546350 | 0.83 | FKBP1A (0.64) | ALDH1A1PDK2FKBP1AKMT2AL3MBTL1 | |
| SCHEMBL3546353 | 0.83 | FKBP1A (0.64) | ALDH1A1PDK2FKBP1AKMT2AL3MBTL1 | |
| SCHEMBL3546372 | 0.82 | PDK2 (0.55) | ALDH1A1PDK2FKBP1AROCK2KMT2A | |
| SCHEMBL3546371 | 0.82 | PDK2 (0.55) | ALDH1A1PDK2FKBP1AROCK2KMT2A | |
| SCHEMBL15596155 | 0.81 | FKBP1A (0.62) | ALDH1A1PDK2FKBP1AROCK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | ALDH1A1 2309/4885PDK2 2445/4885FKBP1A 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.