Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144844 | 0.91 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17448864 | 0.88 | THRB (0.59) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11659781 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1HTTTDP1 | |
| SCHEMBL56496 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL996289 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL347487 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5535254 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15870307 | 0.86 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11133136 | 0.86 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3410733 | 0.86 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1093 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836145-B | Polymerizable photochromic compound and application thereof | 重庆蕾明视光科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117924612-A | Corneal contact lens and silicone contact lens | 望隼科技股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-11945180-B2 | Method of making silicone containing contact lens with reduced amount of diluents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-04-02 | — | — | US | claimed |
| CN-114578582-B | Blazed 5D colorful beauty pupil and preparation method thereof | 江苏海伦隐形眼镜有限公司 | 2024-03-22 | — | — | CN | claimed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | claimed |
| US-20240018309-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-01-18 | — | — | US | claimed |
| CN-117264113-A | Silicone ink-containing intermediate for color contact lens, preparation method thereof and color contact lens | 甘肃康视达科技集团有限公司 | 2023-12-22 | — | — | CN | claimed |
| US-20230364832-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-16 | — | — | US | claimed |
| US-20230357478-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-09 | — | — | US | claimed |
| EP-2038683-A2 | PROCESS FOR MAKING OPHTHALMIC LENSES | Johnson and Johnson Vision Care, Inc. (US) | 2009-03-25 | — | — | EP | claimed |
| WO-2009032267-A2 | CONTACT LENS BASED BIOACTIVE AGENT DELIVERY SYSTEM | UNIVERSITY OF FLORIDA (US) | 2009-03-12 | — | — | WO | claimed |
| WO-2009032266-A2 | DISPERSIONS OF MICROPARTICLES AND MICROGELS IN HYDROGELS FOR DRUG DELIVERY | UNIVERSITY OF FLORIDA (US) | 2009-03-12 | — | — | WO | claimed |
| US-20090060981-A1 | Contact lens based bioactive agent delivery system | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2009-03-05 | — | — | US | claimed |
| WO-2008054651-A2 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-05-08 | — | — | WO | claimed |
| US-20080103231-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2008-05-01 | — | — | US | claimed |
| US-20080075757-A1 | Dispersions of microemulsions in hydrogels for drug delivery | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2008-03-27 | — | — | US | claimed |
| WO-2008005229-A2 | PROCESS FOR MAKING OPHTHALMIC LENSES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-01-10 | — | — | WO | claimed |
| US-20070229757-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. | 2007-10-04 | — | — | US | claimed |
| US-20070222095-A1 | PROCESS FOR MAKING OPHTHALMIC LENSES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-09-27 | — | — | US | claimed |