Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936387 | 0.76 | L3MBTL1 (0.31) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL3068003 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL27858121 | 0.72 | L3MBTL1 (0.34) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL18429007 | 0.72 | CHRM2 (0.35) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL27651002 | 0.72 | MEN1 (0.32) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9547534 | 0.71 | L3MBTL1 (0.36) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8701295 | 0.71 | L3MBTL1 (0.33) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9013395 | 0.70 | ALDH1A1 (0.37) | L3MBTL1 | |
| SCHEMBL4973355 | 0.70 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL28023530 | 0.70 | L3MBTL1 (0.32) | MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219448-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | Myriad Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | claimed |
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | claimed |
| EP-2219448-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | Myriad Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065035-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS | MYRIAD GENETICS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |