Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839095 | 0.89 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3541346 | 0.82 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3543307 | 0.82 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3543406 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3535209 | 0.77 | ANO1 (0.67) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3544726 | 0.76 | ANO1 (0.43) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL10240097 | 0.73 | ANO1 (0.53) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL2841538 | 0.72 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL3545360 | 0.71 | ANO1 (0.63) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL2294234 | 0.71 | L3MBTL1 (0.55) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666863-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2010-02-23 | — | — | US | claimed |