Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548799 | 0.80 | KDM4E (0.49) | L3MBTL1TDP1NPSR1HPGDALDH1A1 | |
| SCHEMBL3547643 | 0.80 | ADORA1 (0.68) | ADORA1MEN1KMT2A | |
| SCHEMBL245593 | 0.79 | ADORA1 (0.64) | NPSR1HPGDALDH1A1MAPTRXFP1 | |
| SCHEMBL3545556 | 0.77 | TDP1 (0.49) | L3MBTL1TDP1NPSR1HPGDALDH1A1 | |
| SCHEMBL13849107 | 0.74 | KDM4E (0.52) | L3MBTL1TDP1NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL28185531 | 0.72 | KDM4E (0.73) | L3MBTL1TDP1NPSR1HPGDALDH1A1 | |
| SCHEMBL11924383 | 0.71 | KDM4E (0.44) | L3MBTL1TDP1NPSR1HPGDALDH1A1 | |
| SCHEMBL13938147 | 0.71 | ADORA1 (0.62) | L3MBTL1NPSR1HPGDALDH1A1MAPT | |
| SCHEMBL244863 | 0.71 | ADORA1 (0.61) | L3MBTL1NPSR1HPGDALDH1A1CYP1A2 | |
| SCHEMBL4031424 | 0.71 | ADORA1 (0.48) | L3MBTL1TDP1NPSR1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-1368319-B1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-20060154969-A1 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
| EP-1368319-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070485-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154969-A1 | Adenosine receptor selective modulators | ADORA2A, ADORA1, ADORA3 | L3MBTL1 4871/4885TDP1 2279/4885NPSR1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.