Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544024 | 0.77 | L3MBTL1 (0.45) | TDP1L3MBTL1NPSR1HPGDRXFP1 | |
| SCHEMBL245321 | 0.76 | ADORA2A (0.60) | NPSR1HPGDRXFP1KDM4EALDH1A1 | |
| SCHEMBL1421642 | 0.76 | SQOR (0.56) | L3MBTL1NPSR1HPGDRXFP1KDM4E | |
| SCHEMBL3547643 | 0.73 | ADORA1 (0.68) | MEN1KMT2AADORA1 | |
| SCHEMBL12681373 | 0.70 | ALDH1A1 (0.55) | NPSR1HPGDRXFP1KDM4EALDH1A1 | |
| SCHEMBL16984845 | 0.70 | ALDH1A1 (0.55) | NPSR1HPGDRXFP1KDM4EALDH1A1 | |
| SCHEMBL7011406 | 0.70 | ADORA2A (0.70) | HPGDRXFP1KDM4EALDH1A1LMNA | |
| SCHEMBL1034013 | 0.68 | ALDH1A1 (0.53) | NPSR1HPGDRXFP1KDM4EALDH1A1 | |
| SCHEMBL19717017 | 0.68 | DNMT1 (0.43) | TDP1L3MBTL1NPSR1HPGDRXFP1 | |
| SCHEMBL16295335 | 0.68 | KDM4E (0.71) | NPSR1HPGDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7825255-B2 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-02 | — | — | US | disclosed |
| EP-1368319-B1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-20060154969-A1 | Adenosine receptor selective modulators | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
| EP-1368319-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070485-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USE AS ADENOSINE RECEPTOR-SELECTIVE LIGANDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154969-A1 | Adenosine receptor selective modulators | ADORA2A, ADORA1, ADORA3 | TDP1 2279/4885L3MBTL1 4871/4885NPSR1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.