Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 12/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.67 |
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | ATM | Q13315 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 4/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.64 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030045 | 0.83 | CYP19A1 (0.75) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5169828 | 0.83 | CYP19A1 (0.75) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13067106 | 0.83 | CYP19A1 (0.75) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL24589994 | 0.82 | CYP19A1 (0.73) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28447904 | 0.82 | CYP19A1 (0.73) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28089750 | 0.82 | CYP19A1 (0.73) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28712885 | 0.82 | CYP19A1 (0.73) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9334035 | 0.81 | CYP19A1 (0.75) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29767702 | 0.81 | CYP19A1 (0.75) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13869506 | 0.81 | CYP19A1 (0.86) | CYP19A1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373813-A | Coumarin Schiff base probe and preparation and application thereof | 陕西学前师范学院 | 2024-07-23 | — | — | CN | claimed |
| CN-110028473-B | Fluorescent probe for detecting polarity of lipid droplets | 济南大学 | 2021-07-27 | — | — | CN | claimed |
| CN-110028956-B | Fluorescent probe for detecting polarity of lipid droplets and application thereof | 济南大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108912084-B | Carbon monoxide fluorescent probe and preparation method and application thereof | 济南大学 | 2020-04-17 | — | — | CN | claimed |
| CN-110028473-A | A kind of polar fluorescence probe of detection fat drips | 济南大学 | 2019-07-19 | — | — | CN | claimed |
| CN-110028956-A | A kind of polar fluorescence probe of detection fat drips and its application | 济南大学 | 2019-07-19 | — | — | CN | claimed |
| CN-118373813-A | Coumarin Schiff base probe and preparation and application thereof | 陕西学前师范学院 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373813-A | Coumarin Schiff base probe and preparation and application thereof | 陕西学前师范学院 | 2024-07-23 | — | — | CN | disclosed |
| CN-110028473-B | Fluorescent probe for detecting polarity of lipid droplets | 济南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110028956-B | Fluorescent probe for detecting polarity of lipid droplets and application thereof | 济南大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-108912084-B | Carbon monoxide fluorescent probe and preparation method and application thereof | 济南大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-110028956-A | A kind of polar fluorescence probe of detection fat drips and its application | 济南大学 | 2019-07-19 | — | — | CN | disclosed |
| CN-110028473-A | A kind of polar fluorescence probe of detection fat drips | 济南大学 | 2019-07-19 | — | — | CN | disclosed |
| US-7745229-B2 | Chemoselective fluorgenic molecular linkers and methods for their preparation and use | UNIVERSITY OF SOUTH CAROLINA | 2010-06-29 | — | — | US | disclosed |
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-09-27 | — | — | US | disclosed |
| WO-2005103705-A2 | CHEMOSELECTIVE FLUOROGENIC MOLECULAR LINKERS AND METHODS OF THEIR PREPARATION AND USE | UNIVERSITY OF SOUTH CAROLINA (US) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224695-A1 | Chemoselective Fluorgenic Molecular Linkers and Methods for Their Preparation and Use | KIT, HLCS, ALK | CYP19A1 3815/4885MEN1 418/4885KMT2A 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.