SCHEMBL5169828

SCHEMBL5169828

CCN(CC)c1ccc2cc(C)c(=O)oc2c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.75
MEN1 O00255 10/20 0.68
KMT2A Q03164 10/20 0.68
KDM4E B2RXH2 10/20 0.68
ALDH1A1 P00352 10/20 0.68
MAPT P10636 9/20 0.68
HPGD P15428 5/20 0.68
NPSR1 Q6W5P4 3/20 0.68
ATM Q13315 6/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
HSD17B10 Q99714 5/20 0.66
MAOB P27338 3/20 0.66
USP2 O75604 3/20 0.66
ALOX15 P16050 2/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2C19 P33261 1/20 0.66
SLC16A3 O15427 1/20 0.66
SLC16A1 P53985 1/20 0.66
L3MBTL1 Q9Y468 5/20 0.65
GLA P06280 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16284305 0.88 ALDH1A1 (0.61) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL2030045 0.84 CYP19A1 (0.75) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL13067106 0.84 CYP19A1 (0.75) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL28447904 0.83 CYP19A1 (0.73) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL3546791 0.83 CYP19A1 (0.73) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL24589994 0.83 CYP19A1 (0.73) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL28712885 0.83 CYP19A1 (0.73) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL28089750 0.83 CYP19A1 (0.73) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL25842366 0.82 SLC16A3 (0.63) CYP19A1MEN1KMT2AKDM4EALDH1A1
SCHEMBL13869506 0.82 CYP19A1 (0.86) CYP19A1MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4402236-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS Reckitt Benckiser Vanish B.V. (NL) 2024-07-24 EP disclosed
WO-2024073568-A2 EVOLUTION OF FLUOROGENIC SENSORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-04 WO disclosed
WO-2023041739-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS RECKITT BENCKISER VANISH B.V. (NL) 2023-03-23 WO disclosed
US-11174281-B1 Modified nucleotides and uses thereof Singular Genomics Systems, Inc. (US) 2021-11-16 US disclosed
WO-2021216998-A1 MODIFIED NUCLEOTIDES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2021-10-28 WO disclosed
US-20210300937-A1 Novel Labelled Cannabinergic Ligands and Related Analogs MAKRIYANNIS ALEXANDROS (US) 2021-09-30 US disclosed
EP-3863550-A1 METHODS, DEVICES, AND COMPOSITIONS FOR MEASURING AND INDUCING CELL-TO-CELL COMMUNICATION, AND THERAPEUTIC USES THEREOF Immunolight, Llc. (US) 2021-08-18 EP disclosed
WO-2020193765-A1 METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING USING PHOTOSWITCHABLE LABELS ILLUMINA CAMBRIDGE LIMITED (GB) 2020-10-01 WO disclosed
US-10745393-B2 Small molecular probes, processes and use thereof JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2020-08-18 US disclosed
WO-2020058339-A1 COUMARIN-BASED CROSSLINKING REAGENTS VENTANA MEDICAL SYSTEMS, INC. (US) 2020-03-26 WO disclosed
WO-2002046252-A1 IRRADIATION CURABLE, HIGH SOLID COATING COMPOSITIONS AND THEIR PREPARATION RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2002-06-13 WO disclosed
EP-0489836-B1 LIGHT ACTIVATED ACYL-ENZYMES UNIV DUKE (US) 1994-12-21 EP disclosed
EP-0260823-B1 IMPROVEMENTS IN OR RELATING TO PRINTING PLATE PRECURSORS E.I. du Pont de Nemours and Company (US) 1993-06-09 EP disclosed
US-5218137-A Chemical light amplifiers DUKE UNIVERSITY (US) 1993-06-08 US disclosed
EP-0489836-A4 LIGHT ACTIVATED ACYL-ENZYMES 1993-05-26 EP disclosed
EP-0489836-A1 LIGHT ACTIVATED ACYL-ENZYMES. UNIV DUKE (US) 1992-06-17 EP disclosed
US-5114851-A Serine- or cysteine-containing protease modified by nucleophilic cinnamic acid; photoisomerization; biological switches; medical diagnosis DUKE UNIVERSITY (US) 1992-05-19 US disclosed
WO-1991003549-A1 LIGHT ACTIVATED ACYL-ENZYMES DUKE UNIVERSITY (US) 1991-03-21 WO disclosed
US-4999271-A Photopolymerizable urethane acrylate or methacrylate, lithography VICKERS PLC (GB) 1991-03-12 US disclosed
EP-0260823-A2 Improvements in or relating to printing plate precursors E.I. du Pont de Nemours and Company (US) 1988-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745393-B2 Small molecular probes, processes and use thereof APBA1, APP, PRNP CYP19A1 4687/4885MEN1 1123/4885KMT2A 3252/4885
US-11174281-B1 Modified nucleotides and uses thereof NUDT1, RNMT, ADAR CYP19A1 3552/4885MEN1 2915/4885KMT2A 1548/4885
US-20210300937-A1 Novel Labelled Cannabinergic Ligands and Related Analogs CNR1, CNR2, CHRND CYP19A1 2393/4885MEN1 4141/4885KMT2A 4575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.