⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265 | 1.00 | — | — | |
| SCHEMBL4361145 | 1.00 | — | — | |
| SCHEMBL10686077 | 0.84 | ALDH1A1 (0.43) | — | |
| Nitric Acid SCHEMBL9158721 | 0.83 | CA5A (0.36) | — | |
| SCHEMBL18194644 | 0.81 | — | — | |
| SCHEMBL50962 | 0.81 | — | — | |
| SCHEMBL4658756 | 0.81 | — | — | |
| SCHEMBL12045201 | 0.79 | — | — | |
| SCHEMBL51837 | 0.79 | — | — | |
| SCHEMBL928477 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-12-14 | — | — | US | disclosed |
| US-11464853-B2 | Amino acid and peptide conjugates and conjugation process | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-10-11 | — | — | US | disclosed |
| US-20220133713-A1 | SIGMA-2 RECEPTOR BINDERS AND THEIR METHOD OF USE | Temple University--of the Commonwealth System of Higher Education | 2022-05-05 | — | — | US | disclosed |
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-20200361864-A1 | Peptide Conjugates, Conjugation Process, and Uses Thereof | AUCKLAND UNISERVICES LTD (NZ) | 2020-11-19 | — | — | US | disclosed |
| EP-3676250-A1 | PEPTIDE CONJUGATES, CONJUGATION PROCESS, AND USES THEREOF | Auckland Uniservices Limited (NZ) | 2020-07-08 | — | — | EP | disclosed |
| WO-2017145097-A2 | AMINO ACID AND PEPTIDE CONJUGATES AND CONJUGATION PROCESS | AUCKLAND UNISERVICES LIMITED (NZ) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017145097-A2 | AMINO ACID AND PEPTIDE CONJUGATES AND CONJUGATION PROCESS | AUCKLAND UNISERVICES LIMITED (NZ) | 2017-08-31 | — | — | WO | disclosed |
| US-9422230-B2 | Process for the preparation of an anticonvulsant agent pregabalin hydrochloride | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-23 | — | — | US | disclosed |
| EP-2399916-B1 | Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors | VERTEX PHARMA (US) | 2014-12-10 | — | — | EP | disclosed |
| EP-1854792-B1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7820693-B2 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20090030195-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1854792-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-11-14 | — | — | EP | disclosed |
| WO-2003097624-A1 | PROCESS FOR PREPARING (R)-3,4-EPOXY-1-BUTANOL | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2003-11-27 | — | — | WO | disclosed |
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |