SCHEMBL3548896

SCHEMBL3548896

[CH]=C(Cl)C(Cl)CCCCC

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
OPRM1 P35372 1/20 0.37
FDPS P14324 4/20 0.37
GPR84 Q9NQS5 3/20 0.35
CA1 P00915 2/20 0.35
SPHK1 Q9NYA1 1/20 0.35
FFAR1 O14842 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.34
LAP3 P28838 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3552415 0.93
SCHEMBL960906 0.80 LMNA (0.42) LMNAOPRM1FDPSGPR84CA1
SCHEMBL18419952 0.78 LMNA (0.46) LMNAFDPSGPR84SPHK1FFAR1
SCHEMBL4643412 0.78 LMNA (0.46) LMNAFDPSGPR84SPHK1FFAR1
SCHEMBL749270 0.78 LMNA (0.46) LMNAFDPSGPR84SPHK1FFAR1
SCHEMBL4810939 0.78 LMNA (0.46) LMNAFDPSGPR84SPHK1FFAR1
SCHEMBL9015772 0.78 LMNA (0.46) LMNAFDPSGPR84SPHK1FFAR1
SCHEMBL9278652 0.76 LMNA (0.39) LMNAOPRM1FDPSGPR84CA1
SCHEMBL8868526 0.76 GPR84 (0.45) FDPSGPR84CA1FFAR1ALDH1A1
SCHEMBL11635824 0.76 GPR84 (0.50) LMNAOPRM1FDPSGPR84SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1613607-B1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF SE (DE) 2013-01-09 EP disclosed
US-7741485-B2 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2010-06-22 US disclosed
EP-1501361-B1 3-HETEROARYL SUBSTITUTED 5-METHYLOXYMETHYL ISOXAZOLINES USED AS HERBICIDES BASF SE (DE) 2009-09-30 EP disclosed
US-7381687-B2 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides BASF AKTIENGESELLSCHAFT (DE) 2008-06-03 US disclosed
US-20060211577-A1 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 US disclosed
EP-1613607-A1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF Aktiengesellschaft (DE) 2006-01-11 EP disclosed
US-20050165020-A1 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides BASF AKTIENGESELLSCHAFT (DE) 2005-07-28 US disclosed
WO-2004089914-A1 BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211577-A1 Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds CBR3, CBR1, CNPY2 LMNA 2968/4885OPRM1 1860/4885FDPS 2185/4885
US-20050165020-A1 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides CBR3, DDT, CYP4X1 LMNA 4163/4885OPRM1 584/4885FDPS 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.