SCHEMBL35505

SCHEMBL35505

C=CC(=O)NC(C)(C)C[Na]

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
GAA P10253 1/20 0.31
TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860763 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL8019097 0.81 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL460924 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL7612005 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL903004 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL35470 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL35674 0.78 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL28949902 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL9252889 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL36167 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705390-B2 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2023-11-15 EP claimed
CN-116656329-A Nano polymer gel for water shutoff and profile control 河南易发石油工程技术有限公司 2023-08-29 CN claimed
EP-3141933-B9 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-11-13 EP claimed
US-10386545-B2 Medical devices having homogeneous charge density and methods for making same JOHNSON & JOHNSON VISION CARE, INC. (US) 2019-08-20 US claimed
EP-3141933-B1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2019-05-22 EP claimed
EP-3401342-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care, Inc. (US) 2018-11-14 EP claimed
US-10073192-B2 Polymers and nanogel materials and methods for making and using the same JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-09-11 US claimed
US-20170146695-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2017-05-25 US claimed
US-9612364-B2 Medical devices having homogeneous charge density and methods for making same JOHNSON & JOHNSON VISION CARE, INC. (US) 2017-04-04 US claimed
EP-3141933-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME Johnson & Johnson Vision Care Inc. (US) 2017-03-15 EP claimed
EP-2484705-A2 Polymeric compositions comprising at least one volume excluding polymer Johnson & Johnson Vision Care, Inc. (US) 2012-08-08 EP claimed
EP-2484704-A2 Polymeric compositions comprising at least one volume excluding polymer Johnson & Johnson Vision Care, Inc. (US) 2012-08-08 EP claimed
EP-2484703-A2 Polymeric compositions comprising at least one volume excluding polymer Johnson & Johnson Vision Care, Inc. (US) 2012-08-08 EP claimed
US-7968650-B2 Polymeric compositions comprising at least one volume excluding polymer JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-06-28 US claimed
US-20110118379-A1 INTERVERTEBRAL DISC AND INTRAOCULAR LENS ASTON UNIVERSITY (GB) 2011-05-19 US claimed
EP-2276513-A2 INTERVERTEBRAL DISC AND INTRAOCULAR LENS Aston University (GB) 2011-01-26 EP claimed
WO-2009127844-A2 INTERVERTEBRAL DISC AND INTRAOCULAR LENS ASTON UNIVERSITY (GB) 2009-10-22 WO claimed
US-20080114123-A1 Anionic polymers having sulfonate, sulfate, phosphonate, phosphate or borate grouops capable of acting as osmotic drivers for contact lenses and medical equipment; maintaining a desired water balance by moving water in or out of a substrate; hydration; wetting agents; coatings; stents; bandages JOHNSON & JOHNSON VISION CAR, INC 2008-05-15 US claimed
EP-1918310-A1 Polymeric compositions comprising at least one volume excluding polymer Johnson & Johnson Vision Care, Inc. (US) 2008-05-07 EP claimed
EP-1261563-B1 MULTIFUNCTIONAL ADDITIVE TO CEMENT SLURRIES SOFITECH NV (BE) 2004-08-25 EP claimed