SCHEMBL9252889

SCHEMBL9252889

C=CC(=O)NC(C)(C)CCl

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
GAA P10253 1/20 0.31
TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860763 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL4906709 0.81 KMT2A (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL460924 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL903004 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL7612005 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL3430840 0.79 ALDH1A1 (0.49) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL35470 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL35505 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL35674 0.78 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL36167 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100355949-C Protein crystallization device, protein crystallization method, protein crystallization agent and preparation method thereof MITSUBISHI RAYON CO (JP) 2007-12-19 CN disclosed
CN-101029078-A Gel used for protein crystalling MITSUBISHI RAYON CO (JP) 2007-09-05 CN disclosed
CN-1863946-A Protein crystallization device, protein crystallization method, protein crystallization agent and preparation method thereof MITSUBISHI RAYON CO (JP) 2006-11-15 CN disclosed
US-5382665-A Synthesis of oxazolines and oxazines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1995-01-17 US disclosed