Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546345 | 0.96 | FPR2 (0.39) | XDHDHODHFPR2GPR55PDE4B | |
| SCHEMBL3672746 | 0.91 | SSTR5 (0.39) | DHODHMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL3679361 | 0.91 | SSTR5 (0.32) | XDHDHODHALDH1A1GAASSTR5 | |
| SCHEMBL3678032 | 0.91 | SSTR5 (0.39) | DHODHMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL3677746 | 0.89 | ALDH1A1 (0.33) | XDHDHODHFPR2PDE4BPDE4A | |
| SCHEMBL3674998 | 0.89 | ALDH1A1 (0.33) | XDHDHODHFPR2PDE4BPDE4A | |
| SCHEMBL3672073 | 0.89 | SSTR5 (0.32) | DHODHFPR2ALDH1A1GAASSTR5 | |
| SCHEMBL3551039 | 0.88 | SMN1; SMN2 (0.42) | FPR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3669519 | 0.88 | ALDH1A1 (0.32) | XDHDHODHPDE4BPDE4APDE4C | |
| SCHEMBL3677475 | 0.88 | ALDH1A1 (0.32) | XDHDHODHPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825147-B2 | Inhibitors of phosphodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-02 | — | — | US | disclosed |
| EP-1663999-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES, LTD. (IN) | 2006-06-07 | — | — | EP | disclosed |
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | US | disclosed |
| WO-2005021515-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | PDE7A, PDE4A, PDE4B | XDH 291/4885DHODH 909/4885FPR2 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.