Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695285 | 0.86 | CYP11B2 (0.52) | POLBNPC1ALDH1A1RAB9AGRIN1 | |
| SCHEMBL10284530 | 0.86 | SYK (0.44) | POLBALDH1A1MAPTGRIN1GRIN2B | |
| SCHEMBL31141582 | 0.85 | POLB (0.48) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL357857 | 0.83 | PDE10A (0.48) | POLB | |
| SCHEMBL357048 | 0.83 | POLB (0.43) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10284671 | 0.83 | POLB (0.43) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4398672 | 0.82 | POLB (0.43) | POLBALDH1A1GRIN1GRIN2B | |
| SCHEMBL116863 | 0.82 | POLB (0.43) | POLB | |
| SCHEMBL115623 | 0.82 | POLB (0.43) | POLB | |
| SCHEMBL175248 | 0.82 | POLB (0.43) | POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424856-B1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-8461181-B2 | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8461181-B2 | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8273764-B2 | Fused heterocyclic compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8273764-B2 | Fused heterocyclic compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-07-12 | — | — | US | disclosed |
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-07-12 | — | — | US | disclosed |
| WO-2012057265-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057266-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057269-A1 | HARMFUL ANIMAL CONTROL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL ANIMALS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057264-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057273-A1 | HARMFUL ANIMAL CONTROL COMPOSITION AND METHOD FOR CONTROLLING HARMFUL ANIMALS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057260-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012057268-A1 | PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PESTS | 住友化学株式会社 (JP) | 2012-05-03 | — | — | WO | disclosed |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178779-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | C3AR1, C9, C5 | POLB 4724/4885MEN1 637/4885KMT2A 1877/4885 |
| US-20120015975-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | C3AR1, C9, C5 | POLB 4724/4885MEN1 637/4885KMT2A 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.