Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.66 |
| ▸ | AURKB | Q96GD4 | 14/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131202 | 0.89 | HDAC1 (0.84) | HDAC1AURKB | |
| SCHEMBL1061039 | 0.79 | HDAC1 (1.00) | HDAC1AURKB | |
| SCHEMBL211110 | 0.77 | HDAC1 (0.80) | HDAC1AURKB | |
| SCHEMBL11918277 | 0.76 | CYP3A4 (0.52) | HDAC1 | |
| SCHEMBL213280 | 0.75 | HDAC1 (0.85) | HDAC1AURKB | |
| SCHEMBL6131078 | 0.74 | AURKB (0.79) | HDAC1AURKBLRRK2 | |
| SCHEMBL210488 | 0.72 | HDAC1 (0.64) | HDAC1AURKB | |
| SCHEMBL8350666 | 0.72 | AURKB (0.78) | HDAC1AURKBLRRK2 | |
| SCHEMBL2733826 | 0.72 | HDAC1 (0.79) | HDAC1 | |
| SCHEMBL213867 | 0.71 | HDAC1 (0.86) | HDAC1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-20060058298-A1 | Inhibitors of histone deacetylase | METHYLGENE, INC. | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058298-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC3 | HDAC1 1/4885AURKB 592/4885LRRK2 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.