Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 6/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554320 | 0.92 | SLC16A3 (0.73) | SLC16A3AKR1C3SMN1; SMN2HTTNPSR1 | |
| SCHEMBL3563076 | 0.92 | SLC16A3 (0.69) | SLC16A3AKR1C3SMN1; SMN2HTTNPSR1 | |
| SCHEMBL7311403 | 0.89 | AKR1C3 (0.85) | SLC16A3AKR1C3SMN1; SMN2POLBPFKFB3 | |
| SCHEMBL3553555 | 0.88 | HTR6 (0.67) | SLC16A3AKR1C3POLBPFKFB3MEN1 | |
| SCHEMBL3557572 | 0.88 | SLC16A3 (0.67) | SLC16A3AKR1C3SMN1; SMN2HTTNPSR1 | |
| SCHEMBL3558114 | 0.87 | POLB (0.67) | SLC16A3AKR1C3POLBPFKFB3MEN1 | |
| SCHEMBL3564982 | 0.86 | POLB (0.74) | SLC16A3AKR1C3POLBPFKFB3MEN1 | |
| SCHEMBL3556736 | 0.85 | SLC16A3 (1.00) | SLC16A3AKR1C3MRGPRX4KMT2A | |
| SCHEMBL3562390 | 0.83 | POLB (0.62) | SLC16A3AKR1C3POLBMEN1KMT2A | |
| SCHEMBL3555622 | 0.83 | SLC16A3 (0.72) | SLC16A3POLBPFKFB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | SLC16A3 425/4885AKR1C3 23/4885SMN1; SMN2 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.