Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 3/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552980 | 1.00 | ADCY8 (0.42) | ADCY8ADCY1PDK2HCRTR1HCRTR2 | |
| SCHEMBL3545842 | 0.93 | HCRTR1 (0.46) | ADCY8ADCY1PDK2HCRTR1HCRTR2 | |
| SCHEMBL3545845 | 0.93 | HCRTR1 (0.46) | ADCY8ADCY1PDK2HCRTR1HCRTR2 | |
| SCHEMBL3544517 | 0.92 | PDK2 (0.44) | PDK2HCRTR1HCRTR2RHOAUSP2 | |
| SCHEMBL5271173 | 0.92 | PDK2 (0.44) | PDK2HCRTR1HCRTR2RHOAUSP2 | |
| SCHEMBL3544857 | 0.89 | HCRTR1 (0.41) | ADCY8ADCY1HCRTR1HCRTR2RHOA | |
| SCHEMBL3544853 | 0.89 | HCRTR1 (0.41) | ADCY8ADCY1HCRTR1HCRTR2RHOA | |
| SCHEMBL3547423 | 0.83 | LMNA (0.47) | PDK2PHGDH | |
| SCHEMBL3547425 | 0.83 | LMNA (0.47) | PDK2PHGDH | |
| SCHEMBL3543791 | 0.83 | HCRTR1 (0.46) | ADCY8ADCY1HCRTR1HCRTR2RHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691843-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | VICURON HOLDINGS LLC | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058304-A1 | N-hydroxyamide derivatives possessing antibacterial activity | AMDHD2, OGA, ENGASE | ADCY8 1481/4885ADCY1 2964/4885PDK2 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.