Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 4/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554975 | 0.92 | KMT2A (0.62) | MEN1GAAKMT2ASERPINE1ACLY | |
| SCHEMBL3552616 | 0.90 | AR (0.55) | MEN1KMT2ASERPINE1MCL1ACLY | |
| SCHEMBL3561240 | 0.89 | KMT2A (0.51) | MEN1GAAKMT2ASERPINE1PPARG | |
| SCHEMBL3562298 | 0.85 | MEN1 (0.62) | MEN1GAAKMT2AACLY | |
| SCHEMBL3556577 | 0.85 | HDAC1 (0.60) | MEN1KMT2AMCL1BCL2A1HDAC4 | |
| SCHEMBL3556578 | 0.84 | PSEN1 (0.52) | MEN1GAAKMT2ASERPINE1PPARG | |
| SCHEMBL3564979 | 0.83 | SERPINE1 (0.51) | MEN1GAAKMT2ASERPINE1PPARG | |
| SCHEMBL3562024 | 0.82 | SLC16A3 (0.58) | MEN1KMT2AGPR27AVPR2AR | |
| SCHEMBL3561412 | 0.81 | PGR (0.54) | MEN1KMT2AMCL1BCL2A1PGR | |
| SCHEMBL3564989 | 0.81 | PTPN5 (0.57) | MEN1KMT2ASERPINE1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | MEN1 2548/4885GAA 1191/4885KMT2A 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.