Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556665 | 1.00 | KDM4E (0.51) | KDM4EKMT2AKDM4AKDM4CTSHR | |
| SCHEMBL28744685 | 1.00 | KDM4E (0.51) | KDM4EKMT2AKDM4AKDM4CTSHR | |
| SCHEMBL17652250 | 0.84 | CYP1A2 (0.63) | KDM4EKMT2APIM1TP53MAPK1 | |
| SCHEMBL28434055 | 0.82 | CYP1A2 (0.64) | KDM4EKDM4AKDM4CTSHRLMNA | |
| SCHEMBL5935781 | 0.80 | ALDH1A1 (0.57) | KDM4EKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL27906900 | 0.77 | ALDH1A1 (0.65) | KDM4EKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL14452075 | 0.77 | ALDH1A1 (0.65) | KDM4EKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL27906903 | 0.77 | ALDH1A1 (0.65) | KDM4EKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL14106874 | 0.77 | ALDH1A1 (0.65) | KDM4EKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL847651 | 0.76 | KDM4E (0.65) | KDM4EKMT2ATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807668-B2 | Anti-inflammatory compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2010-10-05 | — | — | US | disclosed |
| US-20070265253-A1 | Anti-Inflammatory Compounds | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-11-15 | — | — | US | disclosed |
| EP-1789422-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006031134-A1 | ANTI-INFLAMMATORY COMPOUNDS | NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED (NZ) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265253-A1 | Anti-Inflammatory Compounds | TNF, PTGS1, PTGES | KDM4E 3502/4885KMT2A 4755/4885KDM4A 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.