Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11647687 | 0.90 | — | — | |
| Ether SCHEMBL626639 | 0.90 | ALDH1A1 (0.41) | — | |
| Ether SCHEMBL18173787 | 0.90 | ALDH1A1 (0.41) | — | |
| Ether SCHEMBL9788394 | 0.90 | — | — | |
| Ether SCHEMBL9809003 | 0.90 | — | — | |
| Ether SCHEMBL10629462 | 0.90 | — | — | |
| Ether SCHEMBL11648502 | 0.90 | ALDH1A1 (0.41) | — | |
| Ether SCHEMBL10501726 | 0.90 | ALDH1A1 (0.41) | — | |
| Ether SCHEMBL7632694 | 0.90 | — | — | |
| Ether SCHEMBL9788714 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503620-B | Preparation method of 5- (2-oxo-tetrahydrothienoimidazole-4 (2H) -alkenyl) pentanoic acid compound | 浙江新和成股份有限公司 | 2020-10-16 | — | — | CN | claimed |
| EP-3762392-B1 | THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | WELLMARKER BIO CO LTD (KR) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023138524-A1 | KRAS G12D DEGRADATION AGENT AND MEDICAL USE THEREOF | 贝达药业股份有限公司 | 2023-07-27 | — | — | WO | disclosed |
| US-20230172914-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | WELLMARKER BIO CO., LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| CN-113735828-B | Compound for targeted degradation of EGFR (epidermal growth factor receptor), and preparation method and application thereof | 南方医科大学 | 2022-10-28 | — | — | CN | disclosed |
| EP-4011885-A1 | OXO-PYRIDINE FUSION RING DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Wellmarker Bio Co., Ltd. (KR) | 2022-06-15 | — | — | EP | disclosed |
| US-20210317133-A1 | THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | WELLMARKER BIO CO., LTD. (KR) | 2021-10-14 | — | — | US | disclosed |
| US-11053249-B2 | Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders | PHILIPPE YVES-REMY SIMON (FR) | 2021-07-06 | — | — | US | disclosed |
| EP-3819300-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | Wellmarker Bio Co., Ltd. (KR) | 2021-05-12 | — | — | EP | disclosed |
| CN-112771053-A | Biomarker-based therapeutic compositions | 伟迈可生物有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-1048039-A | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |
| CN-1048038-A | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |
| US-4755606-A | Imidazolyl-3,5-di-(diphenyl-butylsilyloxy) carboxylic acid ester intermediates | SANDOZ PHARM. CORP. (US) | 1988-07-05 | — | — | US | disclosed |
| US-4740646-A | Preparation of indanes | BASF AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4691052-A | Process for the preparation of pyrethroid acids | S.C. JOHNSON & SON, INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0088223-B1 | MANUFACTURE OF ISOCYANATES | AMERICAN CYANAMID COMPANY (US) | 1985-04-17 | — | — | EP | disclosed |
| EP-0083685-B1 | MANUFACTURE OF DIISOCYANATES | AMERICAN CYANAMID COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |
| EP-0088223-A1 | Manufacture of isocyanates | AMERICAN CYANAMID COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0083685-A1 | Manufacture of diisocyanates | AMERICAN CYANAMID COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4379767-A | Manufacture of isocyanates | AMERICAN CYANAMID COMPANY (US) | 1983-04-12 | — | — | US | disclosed |