Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655008 | 0.98 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHCYP4A11CYP4F2 | |
| SCHEMBL5253878 | 0.98 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHCYP4A11CYP4F2 | |
| SCHEMBL383349 | 0.95 | ALDH1A1 (0.66) | ALDH1A1LMNADHODHCYP4A11CYP4F2 | |
| SCHEMBL2655484 | 0.88 | ALDH1A1 (0.70) | ALDH1A1LMNADHODHCYP4A11CYP4F2 | |
| SCHEMBL28106654 | 0.87 | ALDH1A1 (0.64) | ALDH1A1LMNADHODHTSHRHSD17B10 | |
| SCHEMBL10360804 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4EGLATSHR | |
| SCHEMBL29148965 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHTSHRKMT2A | |
| SCHEMBL5253873 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHKDM4EGLA | |
| SCHEMBL11552750 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHTSHRKMT2A | |
| SCHEMBL3553354 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNADHODHKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | ALDH1A1 61/4885LMNA 2120/4885DHODH 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.