Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.81 |
| ▸ | PDE4A | P27815 | 4/20 | 0.81 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.81 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440046 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL5510164 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL3555816 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL3555873 | 0.99 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL3555869 | 0.99 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL13658117 | 0.94 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL6440437 | 0.93 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL3551034 | 0.93 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL7207684 | 0.92 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL7207679 | 0.92 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671068-B2 | N-(alkoxyalkyl) carbamoyl-substituted 6-phenyl-benzonaphthyridine derivatives and their use as PDE ¾ inhibitors | NYCOMED GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20070208051-A1 | Novel N-(Alkoxyalkyl) Carbamoyl-Substituted 6-Phenyl-Benzonaphthyridine Derivatives and their Use as Pde 3/4 Inhibitors | ALTANA PHARMA AG (DE) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208051-A1 | Novel N-(Alkoxyalkyl) Carbamoyl-Substituted 6-Phenyl-Benzonaphthyridine Derivatives and their Use as Pde 3/4 Inhibitors | PDE3A, PDE4A, PDE5A | PDE4D 7/4885PDE4A 2/4885PDE4B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.