Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.81 |
| ▸ | PDE4A | P27815 | 4/20 | 0.81 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.81 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440046 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL3554997 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL3555816 | 1.00 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL3555873 | 0.99 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL3555869 | 0.99 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL13658117 | 0.94 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL6440437 | 0.93 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL3551034 | 0.93 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL7207684 | 0.92 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CTSHR | |
| Hydrochloric Acid SCHEMBL7207679 | 0.92 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537109-B1 | NOVEL BENZONAPHTHYRIDINES | ALTANA PHARMA AG (DE) | 2007-04-18 | — | — | EP | disclosed |