SCHEMBL355562

SCHEMBL355562

C=CCCC/C=C/COCCOC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.56
ALDH1A1 P00352 6/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
HSD17B10 Q99714 1/20 0.56
CYP3A4 P08684 3/20 0.47
THRB P10828 2/20 0.44
HPGD P15428 1/20 0.43
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
RECQL P46063 1/20 0.34
MAPK1 P28482 1/20 0.33
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
ABCC4 O15439 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353661 1.00 TSHR (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5440233 0.92 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5440237 0.92 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5675420 0.92 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5441923 0.92 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL85756 0.84 TSHR (0.45) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5436266 0.84 EPHX2 (0.38) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5443446 0.83 MAPT (0.37) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5437789 0.83 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10536751 0.82 TSHR (0.35) TSHRALDH1A1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20120065322-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT EVONIK ROEHM GMBH (DE) 2012-03-15 US disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
US-20110318595-A1 COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER EVONIK ROEHM GMBH (DE) 2011-12-29 US disclosed
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT TSHR 2023/4885ALDH1A1 55/4885TP53 4206/4885
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 TSHR 1058/4885ALDH1A1 370/4885TP53 4438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.