Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521906 | 1.00 | CES2 (0.50) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29056490 | 0.85 | CES2 (0.47) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18936130 | 0.78 | CES2 (0.57) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3553076 | 0.77 | CES2 (0.56) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL31749366 | 0.77 | CES2 (0.56) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28013821 | 0.76 | CES1 (0.39) | CES2CES1MAPTTDP1HDAC1 | |
| SCHEMBL4307207 | 0.76 | CES1 (0.61) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5255384 | 0.76 | CES2 (0.50) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29645049 | 0.76 | CES1 (0.61) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29723922 | 0.76 | F2 (0.57) | CES2CES1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369023-B | Synthesis method and application of 2-aryl acrylate | 华南理工大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-114920753-A | 6-fluoro-dihydropyrano [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113402477-B | Monofluoroolefin modified heteroatom cyclolactone or lactam derivative and synthetic method and application thereof | 华南理工大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114369023-A | Synthesis method and application of 2-aryl acrylate | 华南理工大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-113402477-A | Monofluoroolefin modified heteroatom cyclolactone or lactam derivative and synthetic method and application thereof | 华南理工大学 | 2021-09-17 | — | — | CN | disclosed |
| US-7663301-B2 | for use as robust red organic phosphors | GENERAL ELECTRIC COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| WO-2006076247-A2 | PHOSPHORESCENT FLUORENE, ANTHRACENE AND/OR THIOPHENE SUBSTITUTED METALLO- PORPHYRINS AND RELATED COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060152149-A1 | Porphyrin compositions | GENERAL ELECTRIC COMPANY (US) | 2006-07-13 | — | — | US | disclosed |
| CN-1108659-A | Trifluoroisopropenyl zinc reagent and its derivate application | SHANGHAI INST ORGANIC CHEM (CN) | 1995-09-20 | — | — | CN | disclosed |
| CN-1027539-C | Preparation method of fluorine-containing isopropenyl zinc reagent and derivative thereof | SHANGHAI INST ORGANIC CHEM (CN) | 1995-02-01 | — | — | CN | disclosed |
| CN-1051911-A | Trifluoroisopropenyl zinc reagent and derivative, preparation and application thereof | SHANGHAI ORGANIC CHEMESTRY INS (CN) | 1991-06-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060152149-A1 | Porphyrin compositions | ACP1, MMS19, MVD | CES2 4531/4885CES1 4797/4885KDM4E 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.