SCHEMBL355616

SCHEMBL355616

C=CCC/C=C(/CC)N(CC)CCOC(=O)C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL354281 0.85 THRB (0.41) THRBTSHR
SCHEMBL355276 0.80 TSHR (0.41) THRBTSHR
SCHEMBL452568 0.80 TSHR (0.41) THRBTSHR
SCHEMBL354510 0.79 TSHR (0.40) THRBTSHR
SCHEMBL17522087 0.77 THRB (0.46) THRBTSHR
SCHEMBL27707440 0.76 THRB (0.52) THRBTSHR
SCHEMBL355113 0.76 THRB (0.49) THRBTSHR
SCHEMBL1327708 0.75 THRB (0.50) THRBTSHR
SCHEMBL355615 0.74 THRB (0.41) THRBTSHR
SCHEMBL4981730 0.73 THRB (0.49) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20120065322-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT EVONIK ROEHM GMBH (DE) 2012-03-15 US disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT THRB 2750/4885TSHR 2023/4885
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 THRB 1927/4885TSHR 1058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.