SCHEMBL355615

SCHEMBL355615

C=CCC/C=C/CCN(CC)CCOC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
TSHR P16473 4/20 0.40
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2D6 P10635 2/20 0.31
LMNA P02545 2/20 0.31
CYP1A2 P05177 1/20 0.31
MAOA P21397 1/20 0.31
HTR3A P46098 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
BLM P54132 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SCN1A P35498 1/20 0.30
SCN2A Q99250 1/20 0.30
SCN3A Q9NY46 1/20 0.30
CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356395 0.84 THRB (0.41) THRBTSHRMEN1POLBKMT2A
SCHEMBL356396 0.84 THRB (0.41) THRBTSHRMEN1POLBKMT2A
SCHEMBL10697522 0.83 THRB (0.55) THRBTSHRMEN1POLBKMT2A
SCHEMBL354280 0.83 THRB (0.39) THRBTSHRPOLBALDH1A1
SCHEMBL355275 0.83 TSHR (0.40) THRBTSHRMEN1POLBKMT2A
SCHEMBL453097 0.83 TSHR (0.40) THRBTSHRMEN1POLBKMT2A
SCHEMBL354509 0.83 TSHR (0.40) THRBTSHRMEN1POLBKMT2A
SCHEMBL28273630 0.80 THRB (0.55) THRBTSHRMEN1POLBKMT2A
SCHEMBL14874 0.80 THRB (0.55) THRBTSHRMEN1POLBKMT2A
SCHEMBL5455475 0.80 MEN1 (0.50) THRBTSHRMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
US-20120065322-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT EVONIK ROEHM GMBH (DE) 2012-03-15 US disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT THRB 2750/4885TSHR 2023/4885MEN1 1973/4885
US-20110130509-A1 (METH)ACRYLATE MONOMER, POLYMER AND COATING AGENT MGMT, DNMT1, TET1 THRB 1927/4885TSHR 1058/4885MEN1 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.