Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 18/20 | 0.55 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562263 | 0.84 | NOS2 (0.41) | NOS2NOS1 | |
| SCHEMBL3559323 | 0.82 | NOS2 (0.39) | NOS2NOS1 | |
| SCHEMBL3564163 | 0.78 | NOS2 (0.40) | NOS2NOS1 | |
| SCHEMBL3568583 | 0.77 | NOS2 (0.35) | NOS2NOS1CD38 | |
| SCHEMBL3614975 | 0.77 | NOS2 (0.45) | NOS2NOS1 | |
| SCHEMBL3561754 | 0.76 | NOS2 (0.53) | NOS2NOS1CD38 | |
| SCHEMBL3556830 | 0.76 | NOS2 (0.35) | NOS2NOS1CD38 | |
| SCHEMBL3558824 | 0.76 | NOS2 (0.35) | NOS2NOS1CD38 | |
| SCHEMBL3559917 | 0.76 | NOS2 (0.35) | NOS2NOS1CD38 | |
| SCHEMBL3561747 | 0.74 | NOS2 (0.86) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |