Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 15/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 6/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556830 | 0.93 | NOS2 (0.35) | NOS2TSHRNPC1HSD17B10NOS1 | |
| SCHEMBL3559917 | 0.93 | NOS2 (0.35) | NOS2TSHRNPC1HSD17B10NOS1 | |
| SCHEMBL3558824 | 0.93 | NOS2 (0.35) | NOS2TSHRNPC1HSD17B10NOS1 | |
| SCHEMBL3614975 | 0.82 | NOS2 (0.45) | NOS2NOS1 | |
| SCHEMBL3556345 | 0.77 | NOS2 (0.55) | NOS2NOS1CD38 | |
| SCHEMBL3566903 | 0.76 | NOS2 (0.50) | NOS2NOS1 | |
| SCHEMBL3567894 | 0.75 | NOS2 (0.56) | NOS2NOS1 | |
| SCHEMBL3556926 | 0.72 | NOS2 (0.46) | NOS2NOS1 | |
| SCHEMBL3568589 | 0.72 | NOS2 (0.59) | NOS2NOS1 | |
| SCHEMBL3568576 | 0.72 | NOS2 (0.59) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |