Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.80 |
| ▸ | APEX1 | P27695 | 3/20 | 0.80 |
| ▸ | APAF1 | O14727 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.80 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.80 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.80 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.79 |
| ▸ | MMP2 | P08253 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248025 | 0.96 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9481457 | 0.96 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9481450 | 0.96 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL6679698 | 0.96 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9482531 | 0.91 | TDP1 (0.84) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL29408820 | 0.91 | TDP1 (0.84) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9482517 | 0.91 | TDP1 (0.84) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL13403617 | 0.90 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9483015 | 0.90 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9483029 | 0.90 | TDP1 (0.87) | TDP1APEX1APAF1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705142-B2 | Process for the preparation of cefixime | HETERO DRUGS LIMITED (IN) | 2010-04-27 | — | — | US | disclosed |
| US-7705142-B2 | Process for the preparation of cefixime | HETERO DRUGS LIMITED (IN) | 2010-04-27 | — | — | US | disclosed |
| EP-1863822-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | HETERO DRUGS LTD (IN) | 2009-10-14 | — | — | EP | disclosed |
| EP-1863822-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | HETERO DRUGS LTD (IN) | 2009-10-14 | — | — | EP | disclosed |
| US-20080242858-A1 | Process For the Preparation of Cefixime | HETERO DRUGS LIMITED (IN) | 2008-10-02 | — | — | US | disclosed |
| US-20080242858-A1 | Process For the Preparation of Cefixime | HETERO DRUGS LIMITED (IN) | 2008-10-02 | — | — | US | disclosed |
| EP-1863822-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | Hetero Drugs Limited (IN) | 2007-12-12 | — | — | EP | disclosed |
| EP-1863822-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | Hetero Drugs Limited (IN) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103686-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | HETERO DRUGS LIMITED (IN) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006103686-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | HETERO DRUGS LIMITED (IN) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242858-A1 | Process For the Preparation of Cefixime | ACMSD, HAAO, HDHD5 | TDP1 4467/4885APEX1 2863/4885APAF1 3847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.