SCHEMBL3557941

SCHEMBL3557941

CCCCS(=O)(=O)Nc1ccccc1CCc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 3/20 0.56
RARB P10826 2/20 0.47
MRGPRX1 Q96LB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3555142 0.95 SLC16A3 (0.54) SLC16A3
SCHEMBL3559097 0.94 SLC16A3 (0.53) SLC16A3RARB
SCHEMBL3561334 0.87 SLC16A3 (0.61) SLC16A3
SCHEMBL3556511 0.84 SLC16A3 (0.48) SLC16A3
SCHEMBL3564190 0.84 SLC16A3 (0.57) SLC16A3RARB
SCHEMBL3559576 0.84 SLC16A3 (0.69) SLC16A3RARB
SCHEMBL3560398 0.83 SLC16A3 (0.59) SLC16A3
SCHEMBL3558151 0.83 SLC16A3 (0.61) SLC16A3
SCHEMBL3558898 0.82 SLC16A3 (0.63) SLC16A3
SCHEMBL3558724 0.82 LMNA (0.56) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816397-B2 Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes MERCK PATENT GMBH (DE) 2010-10-19 US claimed
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes MERCK PATENT GMBH (DE) 2008-02-21 US claimed
US-7816397-B2 Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes MERCK PATENT GMBH (DE) 2010-10-19 US disclosed
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes MERCK PATENT GMBH (DE) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045483-A1 Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes SLC5A1, ALDH7A1, ASS1 SLC16A3 425/4885RARB 1279/4885MRGPRX1 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.