Diphenylether

Diphenylether

SCHEMBL3558137

CCCCOC(C)=O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.62
ALDH1A1 P00352 4/20 0.62
TSHR P16473 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
HDAC3 O15379 1/20 0.52
NPC1 O15118 1/20 0.50
HPGD P15428 1/20 0.50
CRHBP P24387 1/20 0.50
RAB9A P51151 1/20 0.50
CRHR2 Q13324 1/20 0.50
CYP3A4 P08684 2/20 0.49
MAPK1 P28482 2/20 0.49
PPARA Q07869 1/20 0.49
TP53 P04637 1/20 0.49
HSD17B10 Q99714 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Butyl Ester SCHEMBL27968251 0.90 LTA4H (0.62) LTA4HALDH1A1TSHRTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL2465806 0.88 ALDH1A1 (0.60) LTA4HALDH1A1TSHRTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL27934470 0.85 ALDH1A1 (0.86) ALDH1A1TSHRTDP1L3MBTL1HPGD
Acetic Acid Butyl Ester SCHEMBL27483284 0.84 ALDH1A1 (0.64) LTA4HALDH1A1TSHRTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL20540736 0.84 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1HPGD
Acetic Acid Butyl Ester SCHEMBL28219232 0.84 ALDH1A1 (0.64) LTA4HALDH1A1TSHRTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL302627 0.84 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1HPGD
Acetic Acid Butyl Ester SCHEMBL9577010 0.84 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1HPGD
Acetic Acid Butyl Ester SCHEMBL8464588 0.84 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1HPGD
Naphthalene SCHEMBL28085391 0.84 ALDH1A1 (0.69) ALDH1A1TSHRTDP1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7649091-B2 complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers EUKARION, INC. (US) 2010-01-19 US claimed
CN-104321395-B aqueous coating composition and method for forming coating film 关西涂料株式会社 2018-03-20 CN disclosed
CN-104136134-B MULTILAYER FILM-FORMING METHOD AND COATED ARTICLE 关西涂料株式会社 2017-05-10 CN disclosed