Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364852 | 0.88 | KMT2A (0.46) | SMN1; SMN2MEN1KMT2AMMP8ALDH1A1 | |
| SCHEMBL7733774 | 0.87 | MAPT (0.55) | SIGMAR1MEN1KMT2ATSHRMAPT | |
| SCHEMBL7733778 | 0.87 | MAPT (0.55) | SIGMAR1MEN1KMT2ATSHRMAPT | |
| SCHEMBL22769344 | 0.86 | HDAC3 (0.51) | SMN1; SMN2SIGMAR1MEN1KMT2AHDAC3 | |
| SCHEMBL30929593 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2SIGMAR1MEN1KMT2AMMP8 | |
| SCHEMBL1878485 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2SIGMAR1MEN1KMT2AMMP8 | |
| SCHEMBL1878484 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2SIGMAR1MEN1KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL27396543 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2SIGMAR1MEN1KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL27723691 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2SIGMAR1MEN1KMT2AMMP8 | |
| SCHEMBL21275440 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087485-A1 | 4-AMINOPIPERIDINE DERIVATIVES | BOEHRINGER MARKUS | 2010-04-08 | — | — | US | disclosed |
| US-7683079-B2 | 4-aminopiperidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20060135561-A1 | 4-Aminopiperidine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087485-A1 | 4-AMINOPIPERIDINE DERIVATIVES | DPP4, GPR119, IAPP | SMN1; SMN2 2081/4885SIGMAR1 119/4885MEN1 3888/4885 |
| US-20060135561-A1 | 4-Aminopiperidine derivatives | DPP4, GPR119, IAPP | SMN1; SMN2 2081/4885SIGMAR1 119/4885MEN1 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.