Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558326 | 0.88 | SMN1; SMN2 (0.52) | KMT2ANPC1RAB9ASMN1; SMN2MMP8 | |
| SCHEMBL29176962 | 0.84 | SMN1; SMN2 (0.45) | KMT2ANPC1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL29176940 | 0.78 | TAS1R3 (0.44) | SMN1; SMN2HPGDALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL8432948 | 0.76 | MEN1 (0.46) | KMT2ANPC1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL5705148 | 0.76 | KMT2A (0.74) | KMT2AGLANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7733778 | 0.74 | MAPT (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL7733774 | 0.74 | MAPT (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL11183460 | 0.74 | SCN1A (0.44) | HPGDALDH1A1 | |
| SCHEMBL10087662 | 0.74 | ALDH1A1 (0.47) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2504506 | 0.74 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |