SCHEMBL3558406

SCHEMBL3558406

[CH2]CCCC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
TSHR P16473 2/20 0.37
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC3 O15379 1/20 0.35
STING1 Q86WV6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2D6 P10635 1/20 0.33
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CA14 Q9ULX7 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4741052 0.93 EPHX2 (0.41) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL4739770 0.91 EPHX2 (0.43) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL4743537 0.91 EPHX2 (0.43) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL4739473 0.91 EPHX2 (0.43) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL2802412 0.86 HDAC6 (0.37) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL1639757 0.85 TSHR (0.50) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL134923 0.85 EPHX2 (0.46) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL2380206 0.83 EPHX2 (0.49) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL14482131 0.83 EPHX2 (0.49) EPHX2TSHRHDAC1HDAC2HDAC6
SCHEMBL20450540 0.83 EPHX2 (0.49) EPHX2TSHRHDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558654-A4 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-04-05 EP claimed
EP-1558654-A2 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF Fujifilm Electronic Materials USA, Inc. (US) 2005-08-03 EP claimed
US-6916543-B2 Copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. (US) 2005-07-12 US claimed
US-20040137362-A1 Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. 2004-07-15 US claimed
WO-2004040371-A2 NOVEL COPOLYMER AND PHOTORESIST COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2004-05-13 WO claimed
CN-113056475-A9 Deprotection method for peptide compound or amide compound and resin removal method in solid phase reaction and method for producing peptide compound 中外制药株式会社 2021-11-23 CN disclosed
CN-113056475-A Deprotection method for peptide compound or amide compound and resin removal method in solid phase reaction and method for producing peptide compound 中外制药株式会社 2021-06-29 CN disclosed
CN-108456154-A A kind of preparation method of N- tertbutyloxycarbonyls alkyl guanidine 昆明理工大学 2018-08-28 CN disclosed
US-9045465-B1 3-heterocyclyl-substituted benzoyl derivatives BASF SE (DE) 2015-06-02 US disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed
CN-104003986-A Pyridine-fused ring compounds, and preparation method, medicinal composition and use thereof SHANGHAI INST MATERIA MEDICA 2014-08-27 CN disclosed
CN-103193687-A Method for preparing sulfonyl chloride in environment-friendly mode UNIV BEIJING CHEMICAL 2013-07-10 CN disclosed
US-4409217-A ANTIMICROBIAL, ANTIBIOTIC FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-11 US disclosed
EP-0088385-A2 7-Acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-14 EP disclosed
US-4400379-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-08-23 US disclosed
US-4399133-A ADMINISTERING, INFECTIONS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-08-16 US disclosed
US-4393059-A BACTERICIDAL CEPHALOSPORINS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-07-12 US disclosed
EP-0057422-A2 New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-08-11 EP disclosed
EP-0048915-A2 New cephem compounds, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-04-07 EP disclosed
US-4294960-A 7-[2-(2-Aminothiazol-4-yl)-2-cyclopentyloxyiminoacetamido]-3-cephem-4-carboxylic acid (synisomer) FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-10-13 US disclosed