Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722998 | 1.00 | KMT2A (0.50) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL22722989 | 1.00 | KMT2A (0.50) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL22758130 | 0.83 | MEN1 (0.49) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL6950057 | 0.82 | CYP2D6 (0.57) | KMT2ACYP2D6HIF1ACYP2C9CYP1A2 | |
| SCHEMBL28833142 | 0.81 | CYP2D6 (0.43) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL28905915 | 0.79 | CYP2C9 (0.58) | CYP2D6HIF1ACYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11168281 | 0.77 | KMT2A (0.50) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL10607689 | 0.76 | CYP2D6 (0.70) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL11090887 | 0.76 | MEN1 (0.45) | KMT2AMEN1CYP2D6HIF1ACYP2C9 | |
| SCHEMBL5307865 | 0.76 | CYP2D6 (0.70) | KMT2AMEN1CYP2D6HIF1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689667-B | Porous chiral material and use thereof | 南开大学 | 2022-07-12 | — | — | CN | disclosed |
| US-10857517-B2 | Porous chiral materials and uses thereof | NANKAI UNIVERSITY (CN) | 2020-12-08 | — | — | US | disclosed |
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1595867-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857517-B2 | Porous chiral materials and uses thereof | ANXA7, XDH, OPRM1 | KMT2A 3099/4885MEN1 412/4885CYP2D6 1864/4885 |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MCHR1, MC1R, PRLHR | KMT2A 1378/4885MEN1 768/4885CYP2D6 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.