Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 6/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560873 | 0.96 | MEN1 (0.73) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3561751 | 0.95 | MEN1 (0.72) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL27791538 | 0.86 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3553632 | 0.85 | SLC16A3 (0.68) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3550821 | 0.85 | MEN1 (0.60) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3562163 | 0.85 | SLC16A3 (0.71) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3558537 | 0.84 | TSHR (0.56) | MEN1KMT2AALDH1A1SLC16A3KAT6A | |
| SCHEMBL6541948 | 0.83 | KMT2A (0.80) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3554971 | 0.83 | MEN1 (0.51) | MEN1KMT2AALDH1A1BCL2L1MCL1 | |
| SCHEMBL3560911 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | claimed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | claimed |
| US-7816397-B2 | Phenylcarboxylic acid derivatives and use thereof for the treatment of diabetes | MERCK PATENT GMBH (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | MERCK PATENT GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045483-A1 | Phenylcarboxylic Acid Derivatives and Use Thereof for the Treatment of Diabetes | SLC5A1, ALDH7A1, ASS1 | MEN1 2548/4885KMT2A 4045/4885ALDH1A1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.