Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8818123 | 0.98 | HSD17B10 (0.55) | HSD17B10HPGDTSHRL3MBTL1TDP1 | |
| SCHEMBL10575663 | 0.91 | HPGD (0.49) | HSD17B10HPGDTSHRCYP1A2ALDH1A1 | |
| SCHEMBL10573667 | 0.85 | HSD17B10 (0.47) | HSD17B10HPGDTSHRL3MBTL1TDP1 | |
| SCHEMBL134991 | 0.84 | LMNA (0.56) | HSD17B10HPGDTSHRCYP1A2MEN1 | |
| SCHEMBL30858931 | 0.84 | LMNA (0.56) | HSD17B10HPGDTSHRCYP1A2MEN1 | |
| SCHEMBL3913811 | 0.84 | HPGD (0.44) | HSD17B10HPGDTSHRCYP1A2ALDH1A1 | |
| SCHEMBL11174442 | 0.84 | CYSLTR2 (0.49) | HSD17B10HPGDALDH1A1 | |
| SCHEMBL3909219 | 0.83 | HPGD (0.43) | HSD17B10HPGDTSHRCYP1A2CYP2C19 | |
| SCHEMBL3914949 | 0.83 | HPGD (0.44) | HSD17B10HPGDTSHRL3MBTL1TDP1 | |
| SCHEMBL10573860 | 0.82 | LMNA (0.53) | HPGDTDP1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870578-B1 | THERAPEUTIC COMPOUNDS | C4X DISCOVERY LTD (GB) | 2023-08-16 | — | — | EP | disclosed |
| CN-110922402-B | C-3 iodo-indolizine compound and preparation method thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2020-10-27 | — | — | CN | disclosed |
| CN-110922402-A | C-3 iodo-indolizine compound and preparation method thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2020-03-27 | — | — | CN | disclosed |
| US-20150196889-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS | CANAM BIORESEARCH INC. (CA) | 2015-07-16 | — | — | US | disclosed |
| US-20150196889-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS | CANAM BIORESEARCH INC. (CA) | 2015-07-16 | — | — | US | disclosed |
| US-20150196889-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS | CANAM BIORESEARCH INC. (CA) | 2015-07-16 | — | — | US | disclosed |
| US-8926801-B2 | Methods of electrospray chemical synthesis and device for use therein | CANAM BIORESEARCH INC. (CA) | 2015-01-06 | — | — | US | disclosed |
| US-8926801-B2 | Methods of electrospray chemical synthesis and device for use therein | CANAM BIORESEARCH INC. (CA) | 2015-01-06 | — | — | US | disclosed |
| US-8926801-B2 | Methods of electrospray chemical synthesis and device for use therein | CANAM BIORESEARCH INC. (CA) | 2015-01-06 | — | — | US | disclosed |
| US-20120012453-A1 | METHODS OF ELECTROSPRAY CHEMICAL SYNTHESIS AND DEVICE FOR USE THEREIN | CANAM BIORESEARCH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| EP-0282891-B1 | New thymopentin retro-inverso analogs and fragments thereof, a process of preparation of the new compounds and the intermediates obtained therein | ENIRICERCHE SPA (IT) | 1994-01-26 | — | — | EP | disclosed |
| US-4948873-A | SEX HORMONE REGULATORS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1990-08-14 | — | — | US | disclosed |
| WO-1989011289-A1 | PEPTIDES HAVING T CELL HELPER ACTIVITY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| US-4877795-A | 4H-quinolizin-4-one compounds useful for the treatment of allergic bronchial asthma, allergic rhinitis atropic dermatitis and the like | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0282891-A2 | New thymopentin retro-inverso analogs and fragments thereof, a process of preparation of the new compounds and the intermediates obtained therein | ENIRICERCHE S.p.A. (IT) | 1988-09-21 | — | — | EP | disclosed |
| EP-0277755-A1 | 4H-quinolizin-4-one compounds exhibiting therapeutic activities | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0157753-B1 | NEW SOMATOSTATIN COMPOUNDS, PROCESS FOR THEIR SYNTHESIS, PREPARATION FOR VETERINARY USE CONTAINING SAID COMPOUND AND PROCESS FOR THE TREATMENT OF ANIMALS | TECHLAND, Société Anonyme (BE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0157753-A1 | New somatostatin compounds, process for their synthesis, preparation for veterinary use containing said compound and process for the treatment of animals | TECHLAND, Société Anonyme (BE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0145032-A1 | LH- RH Antagonists | AKZO N.V. (NL) | 1985-06-19 | — | — | EP | disclosed |
| US-4064233-A | ANTIBACTERIAL, GROWTH STIMULANT | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |