SCHEMBL134991

SCHEMBL134991

CCOC(=O)Cc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 2/20 0.50
CYP1A2 P05177 1/20 0.49
TSHR P16473 1/20 0.49
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HSD17B10 Q99714 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30858931 1.00 LMNA (0.56) LMNAALDH1A1KDM4ECYP1A2TSHR
Fluorene SCHEMBL28058685 0.87 GABRP (0.52) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL10575663 0.87 HPGD (0.49) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL11174442 0.86 CYSLTR2 (0.49) LMNAALDH1A1HSD17B10HPGD
SCHEMBL3917973 0.85 LMNA (0.46) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL356002 0.84 HSD17B10 (0.56) ALDH1A1KDM4ECYP1A2TSHRRAB9A
Methyl Alcohol SCHEMBL3396777 0.84 ALDH1A1 (0.53) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL3912119 0.84 ALDH1A1 (0.43) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL4341122 0.83 LMNA (0.57) LMNAALDH1A1KDM4ECYP1A2TSHR
SCHEMBL7860739 0.83 CTDSP1 (0.66) LMNAALDH1A1KDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 707 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314945-B1 ELECTROCHROMIC ELEMENT, ELECTROCHROMIC DISPLAY DEVICE, ELECTROCHROMIC LIGHT-CONTROLLING DEVICE, AND ELECTROLYTE COMPOSITION RICOH CO LTD (JP) 2025-12-17 EP claimed
US-8735586-B2 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles SANOFI (FR) 2014-05-27 US claimed
EP-2173721-B1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI SA (FR) 2011-12-28 EP claimed
EP-2173747-B1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI SA (FR) 2011-12-21 EP claimed
US-20100261909-A1 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles SANOFI-AVENTIS (FR) 2010-10-14 US claimed
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI-AVENTIS (FR) 2010-08-26 US claimed
EP-2173747-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
EP-2173721-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
WO-2009000413-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI-AVENTIS (FR) 2008-12-31 WO claimed
WO-2009000412-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI AVENTIS (FR) 2008-12-31 WO claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP claimed
US-4948894-A BACTERICIDE INTERMEDIATES AMERICAN CYANAMID COMPANY (US) 1990-08-14 US claimed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US claimed
JP-2049782-A None JP disclosed
US-12630742-B2 Polishing composition using polishing particles containing basic substance and having high water affinity NISSAN CHEMICAL CORPORATION (JP) 2026-05-19 US disclosed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US disclosed
US-3993656-A BRONCHODILATOR, HYPOTENSIVES MERCK & CO., INC. (US) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261909-A1 Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles AZI2, NISCH, UQCRB LMNA 4203/4885ALDH1A1 97/4885KDM4E 1197/4885
US-12630742-B2 Polishing composition using polishing particles containing basic substance and having high water affinity POLR1A, PRMT1, SRRM2 LMNA 978/4885ALDH1A1 4112/4885KDM4E 3297/4885
US-20100216988-A1 Regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles AZI2, NIT2, NISCH LMNA 4786/4885ALDH1A1 107/4885KDM4E 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.