Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 16/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354131 | 1.00 | DHODH (1.00) | DHODHLMNAGAACLCN2MEN1 | |
| Water SCHEMBL356057 | 0.99 | DHODH (0.98) | DHODHLMNAGAACLCN2MEN1 | |
| Tromethamine SCHEMBL16741990 | 0.92 | DHODH (0.85) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL729556 | 0.88 | DHODH (0.81) | DHODHLMNAGAAMEN1NPC1 | |
| SCHEMBL728038 | 0.87 | DHODH (1.00) | DHODHLMNAGAACLCN2MEN1 | |
| SCHEMBL729595 | 0.85 | DHODH (1.00) | DHODHLMNAGAA | |
| SCHEMBL3725645 | 0.84 | DHODH (0.72) | DHODHLMNAGAACLCN2MEN1 | |
| SCHEMBL729195 | 0.81 | DHODH (0.78) | DHODHMEN1NPC1MAPTRAB9A | |
| SCHEMBL729207 | 0.81 | DHODH (1.00) | DHODHLMNAGAACLCN2MEN1 | |
| SCHEMBL12082596 | 0.77 | LMNA (0.78) | DHODHLMNAGAACLCN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120014918-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2012-01-19 | — | — | US | disclosed |
| EP-2406225-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall S.A. (ES) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014918-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | DHODH, DAO, ADH1B | DHODH 1/4885LMNA 3480/4885GAA 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.